Controlled studies where one group is given Vitamin E and the other a placebo have found no significant harm or benefit at reasonable dose levels:
Three other meta-analyses that combined the results of randomized controlled trials designed to evaluate the efficacy of vitamin E supplementation for the prevention or treatment of cardiovascular disease found no evidence that vitamin E supplementation up to 800 IU/day significantly increased or decreased cardiovascular disease mortality or all-cause mortality (73-75). Additionally, a more recent meta-analysis of 57 randomized controlled trials found that vitamin E supplementation, up to doses of 5,500 IU/day, had no effect on all-cause mortality (76). Furthermore, a meta-analysis of 68 randomized trials found that supplemental vitamin E, singly or in combination with other antioxidant supplements, did not significantly alter risk of all-cause mortality (77). At present, there is no convincing evidence that vitamin E supplementation up to 800 IU/day increases the risk of death from cardiovascular disease or other causes.
[The study] reported that adults who took supplements of 400 IU/day or more were 6% more likely to die from any cause than those who did not take vitamin E supplements (72). However, further breakdown of the risk by vitamin E dose and adjustment for other vitamin and mineral supplements revealed that the increased risk of death was statistically significant only at a dose of 2,000 IU/day, which is higher than the UL for adults.
After looking at the first commercials for the iPad, [Steve Jobs] tracked down the copywriter, James Vincent, and told him, "Your commercials suck."
"Well, what do you want?" Vincent shot back. "You've not been able to tell me what you want."
"I don't know," Jobs said. "You have to bring me something new. Nothing you've shown me is even close."
Vincent argued back and suddenly Jobs went ballistic. "He just started screaming at me," Vincent recalled. Vincent could be volatile himself, and the volleys escalated.
When Vincent shouted, "You've got to tell me what you want," Jobs shot back, "You've got to show me some stuff, and I'll know it when I see it."
The Big Bang Theory - watched it all in the past 3 weeks. Sheldon grew on me.
The Office - still good.
The Boss - excellent acting. Sexy and interesting in the way The Wire was for its first 1.5 seasons.
